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SASInstitute A00-282 Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Clinical Trials Process | 5% | - Clinical trial lifecycle and protocol - Derive programming requirements from protocol and CRF |
| Topic 2: Validate Clinical Trial Data Reporting | 20% | - Programming validation techniques - Validation principles - Use PROC COMPARE and log review |
| Topic 3: Clinical Trials Data Structures | 10% | - Clinical domain structures - Define.xml and dataset specifications - CDISC standards: SDTM, ADaM |
| Topic 4: Manage Clinical Trials Data | 5% | - Use SQL and dictionary tables - Clean, merge, and subset data - Access and explore clinical datasets |
| Topic 5: Regulatory Submissions | 5% | - Compliance for clinical data reporting - ICH and FDA guidelines |
| Topic 6: Transform or Summarize Clinical Trials Data | 15% | - Data step manipulation - Aggregation and transposition - Derive variables and study days |
| Topic 7: Apply Statistical Procedures for Clinical Trials | 15% | - Basic statistical analysis for clinical data - PROC MEANS, FREQ, TABULATE |
| Topic 8: Report Clinical Trials Results | 10% | - PROC REPORT and PROC PRINT - Produce tables, listings, and figures |
| Topic 9: Macro Programming for Clinical Trials | 15% | - Create and call macros - Macro variables and parameters - Debugging macros |
SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:
Review the following procedure code:
proc ttest data=DATA1;
class GROUPVAR1;
var VAR1;
run;
Which variable is most appropriate to be analyzed as variable VAR1?
- A. Age, with possible values of any integer between and including 18 and 65
- B. Treatment, with possible values of "Placebo" or "Active"
- C. Systolic blood pressure, with possible values of "<120", "120 - 139", "140 - 159", "160 - 179", and
"180+" - D. Number of infections, with possible values of 0, 1, or 2
Correct Answer: A 🗳️
The following SAS program is submitted:
proc sort data=SASUSER.VISIT out=PSORT; by code descending date cost; run; Which statement is true regarding the submitted program?
- A. The descending option applies to the DATE and COST variables.
- B. The PSORT data set is stored in the SASUSER library.
- C. The variable CODE is sorted by ascending order.
- D. The descending option applies to the variable CODE.
Correct Answer: C 🗳️
Which COMPUTE block correctly completes the code shown below to compute the ratio of the median Length to the median Weight?
proc report data = DM;
columns USUBJID Ratio Length Weight;
define USUBJID / group;
define Ratio / computed;
define Length / analysis median;
define Weight / analysis median;
run;
- A. compute Weight;
Ratio = Length.Median / Weight.Median;
endcomp; - B. compute Ratio;
Ratio = Length.Median / Weight.Median;
endcomp; - C. compute Weight;
Ratio = Length / Weight;
endcomp; - D. compute Ratio;
Ratio = Length/ Weight;
endcomp;
Correct Answer: C 🗳️
The following SAS program is submitted:
proc univariate date=work.STUDY; by VISIT; class REGION TREAT; var HBA1C GLUCOS; run; You want to store all calculated means and standard deviations in one SAS data set.
Which statement must be added to the program?
- A. output mean std;
- B. ods output mean=m1 m2 std=s1 s2;
- C. ods output out=WORK.RESULTS mean=m1 m2 std=s1 s2;
- D. output out=WORK.RESULTS mean=m1 m2 std=s1 s2;
Correct Answer: D 🗳️
Given two data sets with the following variables:
Why is the blue note showing in the log?
- A. There are multiple observations with the same value for SUBJID in both data sets.
- B. One of the two data sets has multiple observations with the same value for SUBJID.
- C. There are no observations with matching values for SUBJID in either data set.
- D. The variable VISIT occurs in both data sets but is not included in the BY statement.
Correct Answer: A 🗳️
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